Kamagra contains the active agent, Sildenafil which is a selective inhibitor of cGMP specific phosphodiesterase 5 (PDE5). Physiological mechanism of erection is the release of nitrogen oxide in cavernous bodies during sexual stimulation. Nitrogen oxide activates enzyme guanylate cyclase, which causes an increase in cGMP level, relaxation of smooth muscles of the cavernous body and an increase in blood flow to them.
Sildenafil does not have a direct relaxing effect on isolated cavernous body; however, it significantly increases the effectiveness of nitrogen oxide by inhibiting PDE5, which is responsible for the breakdown of cGMP in the cavernous body. When local release of NO occurs during sexual stimulation, inhibition of PDE5 by sildenafil leads to an increase in the concentration of cGMP in the cavernous body, as a result of which smooth muscles are relaxed and the flow of blood to the cavernous body increases. The use of sildenafil in recommended doses will be ineffective without sexual stimulation.
Please, note: when using sildenafil at a dose of 100 mg in some patients after 1 hour, a slight transient violation of color discrimination (blue/green) was detected; 2 hours after taking the drug, these disorders disappear. The use of Kamagra is contraindicated to patients with hypersensitivity to the active substance or any other components of the drug. Due to the effect on nitrogen oxide/cGMP exchange, sildenafil enhances the hypotensive effect of nitrates during their single or long-term use, therefore its simultaneous use with nitrogen oxide donors, organic nitrates or organic nitrites in any form is constantly or periodically contraindicated.
Drugs for the treatment of erectile dysfunction, including sildenafil, should not be used in patients for whom sexual activity is undesirable (for example, patients with severe forms of cardiovascular disease, such as unstable angina or severe heart failure). Sildenafil is contraindicated to patients with loss of vision in one eye due to non-arterial anterior ischemic optic neuropathy, regardless of whether this occurred as a result of taking a PDE5 inhibitor or not.
The safety of sildenafil was not studied in such subgroups of patients, and therefore its use is contraindicated: for patients with severe hepatic impairment, arterial hypotension, with recent stroke or myocardial infarction and known hereditary degenerative retinal diseases such as retinitis pigmentosa.
Frequently Asked Questions
1. What are generics?
Generics are copies of medicines issued by pharmaceutical companies that did not develop these remedies, but used ready-made formula. Viagra is a brand name (for the market), its pharmaceutical name is sildenafil. Scientists at Pfizer discovered the substance sildenafil in 1998 and launched it under the name Viagra (this is the original). In 2008, the Indian pharmaceutical company Sunrise Remedies took advantage of the development of Pfizer and released sildenafil under the brand name Kamagra (this is a generic).
2. Is Kamagra different from the original?
It all depends on the manufacturer, but in case of Indian generics, there is no difference. It is clear that the original will always be better than generic, since the original drugs are usually produced by huge pharmaceutical companies with a turnover of billions of dollars. They have better scientists, equipment, and raw materials. But you will have to pay for it accordingly. In India, pharmaceuticals are perfectly developed. They have modern equipment and high-quality raw materials. This gives a good effect, but at the same time, the price remains acceptable. Therefore, generics from India are universally recognized medications.
3. Why is Kamagra cheaper than Viagra?
The cost of the originals includes not only the production cost, but also the cost of research and advertising, and this is not included in the price of generics. Let’s get back to Pfizer and Viagra. The company spent more than $100 million only on the discovery and release of a new facility (and this was back in 1998, when prices for all were ten times lower). Now they annually spend more than $100 million on advertising. Naturally, all these expenses are invested in the total cost of the product. Raw materials and production costs are worth a penny. As you already understood, pharmacists from India avoided such costs, so they can set prices as close to production costs as possible.
4. What is Kamagra packing form, composition and dosage?
Packing is in the form of a blister with 4 tablets. Each Kamagra tablet contains sildenafil (100 mg). Please, note: the manufacturing company changed the packaging design several times: they were blue, red, and now green. The supplier reserves the right to supply the drug in the form in which it will be released by the company on the date of manufacture of the drug without prior notice to the customer and regardless of the image shown on the product card on the website.
5. How to administer Kamagra?
Kamagra is used in the treatment of male sexual disorders. It is prescribed for difficulties in achieving erection and its retention for a sufficient time. Sildenafil in a dose of 100 mg should be taken only on doctor’s prescription. Kamagra is generally administered about one hour before intercourse. When taken on an empty stomach, the effect is faster. Swallow the whole tablet and drink it with little water. A tablet is to be taken not oftener than once a day. To get the most benefit from the drug, you should not drink a large amount of alcohol before taking it.
6. How does Kamagra interact with other drugs?
You should tell your doctor about all the drugs you are taking. Kamagra can be taken with other medicines only if it is recommended by a doctor. Kamagra can cause unwanted effects, an increase in the action of drugs called nitrates and nitrogen oxide donors (used to treat angina pectoris). At the same time, this drug cannot be used in combination with other remedies intended for the treatment of malfunctioning erection.
It is contraindicated to take Kamagra while taking the following medicines:
- Nitroglycerin, isosorbide mononitrate, any other drugs containing nitrates, including poppers
- Sodium nitroprusside
- Amyl nitrate (poppers)
- Antifungal drugs, or antimycotics such as itraconazole, ketoconazole (creams for the treatment of candidiasis / thrush are safe)
- Mibefradil
- Erythromycin
- Cimetidine
- Rifamycin
- Antidepressants SSRIs, SNRI, lithium, tricyclic antidepressants
- Monoamine Oxidase Inhibitors (MAO)
- All drugs of the Serotonin group and agents that primarily affect serotonergic processes, including L-Tryptophan, triptan, tramadol, linezolid, St. John’s wort
- CYP3A4 Inhibitors
7. Are there any contraindications to the application of Kamagra?
In case of an allergic reaction to the drug or its any component (itching, rash, swelling of the face or lips, shortness of breath), you should consult a doctor if you suffer from any of the following conditions: sickle cell anemia, leukemia, multiple myeloma, or a disease or deformation of penis; a rare eye disease called retinitis pigmentosa, stomach ulcers, and bleeding disorders (such as hemophilia).
8. Can I take GKamagra with alcohol?
Alcohol helps to reduce sensitivity and slow down the period of exposure of the drug to male body. Therefore, combining Kamagra and alcohol is not recommended. However, doctors state the fact that the combination of the drug with alcohol in small doses is still allowed. However, in order to minimize all risks, it is advisable to take the drug in its pure form.
9. Can you inform of Kamagra side-effects?
Kamagra can cause a number of adverse reactions: headache and flushing; digestive disorders, dizziness, nasal congestion, change in vision (discoloration of objects, increased brightness of light or blurred vision). These unwanted effects are usually mild and moderate and do not last long.
10. What is Kamagra’s modus operandi?
In its action, Kamagra is in no way inferior to Viagra with a composition of sildenafil 100 mg. Special additives of the Indian manufacturer have made this drug even more effective and convenient for use. After 45 minutes, the man will feel a rush of blood in the genital area. The increased blood supply caused by the action of sildenafil leads to the strengthening of penis and increase of its sensitivity. But such an effect is achieved only if there is a source of inspiration. A pretty woman and Generic Kamagra are two important keys to fill sex with wonderful feelings and pleasant emotions.
11. Can I take more than 1 pill of Kamagra per day?
With an overdose, pronounced side-effects appear. An indication of an overdose can be erection lasting more than four hours. In this case, you need to urgently consult a doctor or call an ambulance. The doctor will wash the stomach, relieve intoxication and symptoms of allergic reactions, prescribe rehabilitation treatment. To avoid overdose, select a dose with your doctor, do not shorten the interval between doses of the drug – it should be at least 24 hours and be careful not to accidentally take more than 1 pill of Generic Kamagra.
12. What are presentation forms of Kamagra?
Kamagra is released in various forms:
- Kamagra 50 mg and 100 mg
- Kamagra Soft 100 mg
- Kamagra Polo 100 mg
- Kamagra Oral Jelly
13. What is so special about Kamagra?
- This generic not only gives an excellent one-time effect, but also strengthens potency and has a positive effect on libido.
- Kamagra has a positive effect on mental health of men.
- Kamagra has a beneficial effect on the urogenital system of men with regular use.
- This effective drug, helps to solve 2 problems at once which is the best choice for men.
14. Is Kamagra more profitable than Viagra?
Among drugs for regulating potency, the most famous was Viagra, which became the first truly working and powerful solution that helps restore a men’s confidence in sexual viability. Today, Viagra has already lost its fame with the appearance of generic drugs on the market, which constitute an alternative to the eminent branded drug. Significant help in the fight against weakness of potency is provided by Kamagra. The medicine helps to improve weakened potency due to age-related effects, as well as caused by pathological changes in the physiological or psychological state. The composition of the medicine contains 100 mg of sildenafil, which effectively cope with severe symptoms of impotency.
15. When should I start using Kamagra?
The main indications for the appointment of the drug are:
- weak blood supply and weakness of erection;
- malfunctions and loss of erection;
- lack of response to arousal (impotency).
Use of tablets is allowed only for its intended purpose and in the absence of contraindications.
16. What is the difference between the original Viagra and Kamagra?
The uniqueness of the chemical formula of Viagra has been confirmed and protected by an international patent. For a long time, Pfizer remained a monopolist in the market for pharmaceuticals of this kind. After the patent protection time expired, the formula of Viagra was disclosed, which led to attempts to recreate success and the emergence of high-quality analogues (generics) of the drug. The composition of Kamagra contains the same active substance – sildenafil citrate. By using this generic to restore erection, a man gets an identical Viagra result for less money. This is due to the fact Pfizer spent enormous amounts of money to develop a unique formula, conduct laboratory tests, patenting, conduct a marketing company to promote new products on the market when creating Viagra. Manufacturers of Kamagra save on these stages creating a cheaper product. It does not mean that analogues are worse and ineffective. On the contrary, in the production of more modern generics, the best raw materials are used, since the requirements for the quality of pharmaceutical preparations are constantly increasing. In addition, copies of Viagra are also subjected to laboratory tests, and the manufacture of tablets at each stage of the technological process is monitored and confirmed by WHO certificates. The difference between Viagra and Generic Kamagra is only in the cost of the finished product.
17. What is the difference between Kamagra, Malegra and Suhagra?
These drugs are high-quality and effective Viagra offered by Indian manufacturers. This means there is no particular difference between Kamagra, Malegra or Suhagra – all these drugs increase potency and contain sildenafil as the active substance. The difference is only in the manufacturer. So, Generic Kamagra is a product developed by Ajanta Pharma Limited, Malegra – by Sunrise Remedies Pvt. Ltd., and Suhagra is a new product from the pharmaceutical company Cipla. All these Viagra analogues are used to treat erectile dysfunction and are effective in the fight against impotence. It must be borne in mind that both Kamagra, Suhagra, and Malegra are able to enhance an erection, but they do not prolong sexual intercourse. For a comprehensive solution to sexual problems, combined preparations based on sildenafil and dapoxetine are recommended.
Disclaimer: The information contained in this article is intended solely for information purposes by the individual or entity, and is not to be considered as a diagnosis or an instruction for treatment without prior consultation by a specialist. Usage of this article as treatment method is prohibited, the website is not responsible for practical application of these data. Always consult a specialist before treatment.